KEGG   Homo sapiens (human): 8078
Entry
8078              CDS       T01001                                 
Symbol
USP5, ISOT
Name
(RefSeq) ubiquitin specific peptidase 5
  KO
K11836  ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    8078 (USP5)
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    8078 (USP5)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    8078 (USP5)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.19  Omega peptidases
    3.4.19.12  ubiquitinyl hydrolase 1
     8078 (USP5)
Peptidases and inhibitors [BR:hsa01002]
 Cysteine peptidases
  Family C19: ubiquitin-specific protease family
   8078 (USP5)
Ubiquitin system [BR:hsa04121]
 Deubiquitinating enzyme (DUB)
  Ubiquitin-specific proteases (UBPs)
   UBP/USP
    8078 (USP5)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   8078 (USP5)
SSDB
Motif
Pfam: UCH zf-UBP_var UBA zf-UBP UCH_1 UBA_4 UBA_3
Other DBs
NCBI-GeneID: 8078
NCBI-ProteinID: NP_001092006
OMIM: 601447
HGNC: 12628
Ensembl: ENSG00000111667
UniProt: P45974 A0A140VJZ1
Structure
Position
12:6852150..6866632
AA seq 858 aa
MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFLGFGKQYVER
HFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDV
KIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHA
FSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRET
GYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDM
NQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEK
IFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKAL
IGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYT
QRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPE
QVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDIS
QLRGTGLQPGEEELPDIAPPLVTPDEPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVI
IQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAA
DPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSA
ADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCAS
EKPPKDLGYIYFYQRVAS
NT seq 2577 nt   +upstreamnt  +downstreamnt
atggcggagctgagtgaggaggcgctgctgtcagtattaccgacgatccgggtccctaag
gctggagaccgggtccacaaagacgagtgcgccttctccttcgacacgccggagtctgag
gggggcctctacatctgtatgaacacgtttctgggctttgggaaacagtatgtggagaga
catttcaataagaccggccagcgagtctacttgcacctccggcggacccggcgcccgaaa
gaggaggaccctgctacaggcactggagacccaccccggaagaagcccacgcggctggct
attggtgttgaaggcggatttgaccttagcgaggagaagtttgaattagacgaggatgtg
aagattgtcattttgccagattacctggagattgcccgggatggactggggggactgcct
gacattgtcagagatcgggtgaccagtgcagtggaggccctactgtcggccgactcagcc
tcccgcaagcaggaggtgcaggcatgggatggggaagtacggcaggtgtctaagcatgcc
ttcagcctcaagcagttggacaaccctgctcgaatccctccctgtggctggaagtgctcc
aagtgtgacatgagagagaacctgtggctcaacctgactgatggctccatcctctgtggg
cgacgctacttcgatggcagtgggggcaacaaccacgctgtggagcactaccgagagaca
ggctacccgttagctgtcaagctgggcaccatcacccctgatggagctgacgtgtactca
tatgatgaggatgacatggtcctggaccccagcctggctgagcacctgtcccacttcggc
atcgacatgctgaagatgcagaagacagacaagacgatgactgagttggagatagacatg
aaccagcggattggtgaatgggagctgatccaggagtcaggtgtgccactcaagcccctg
tttgggcctggctacacaggcatccggaacctgggtaacagctgctacctcaactctgtg
gtccaggtgctcttcagcatccctgacttccagaggaagtatgtggataagctggagaag
atcttccagaatgccccgacggaccctacccaggatttcagcacccaggtggccaagctg
ggccatggccttctctccggggagtattccaagccagtaccggagtcgggcgatggggag
cgggtgccagaacagaaggaagttcaagatggcattgcccctcggatgttcaaggccctc
atcggcaagggccaccctgaattctccaccaaccggcagcaggatgcccaggagttcttc
cttcaccttatcaacatggtggagaggaattgccggagctctgaaaatcctaatgaagtg
ttccgcttcttggtggaggaaaagatcaagtgcctggccacagagaaggtgaagtacacc
cagcgagttgactacatcatgcagctgcctgtgcccatggatgcagcccttaacaaagag
gagcttctggagtacgaggagaagaagcggcaagccgaagaggagaagatggcactgcca
gaactggttcgggcccaggtgcccttcagctcttgcctggaggcctacggggcccctgag
caggtcgatgacttctggagcacggccctgcaggccaagtcagtagctgtcaagaccaca
cgatttgcctcattccctgactacctggtcatccagatcaagaagttcaccttcggctta
gactgggtgcccaagaaactggatgtgtccatcgagatgccagaggagctcgacatctcc
cagttgaggggcacagggctgcagcccggagaggaggagctgccagacattgccccaccc
ctggtcactccggatgagcccaaaggtagccttggtttctatggcaacgaagacgaagac
tccttctgctcccctcacttctcctctccgacatcgcccatgctggatgaatcagtcatc
atccagctggtggagatgggattccctatggacgcctgccgcaaagctgtctactacacg
ggcaacagcggggctgaggccgccatgaactgggtcatgtcacacatggatgatccagat
tttgcaaaccccctcatcctgcctggctctagtgggccgggctccacaagcgcagcagcc
gacccccctcctgaggactgtgtgaccaccattgtctccatgggcttctcccgggaccag
gccttgaaagcgctgcgggccacgaacaatagtttagaacgggctgtggactggatcttc
agtcacattgacgacctggatgctgaagctgccatggacatctcagagggccgctcagct
gccgactccatctctgagtctgtgccagtgggacctaaagtccgggatggtcctggaaag
tatcagctctttgccttcattagtcacatgggcacctctaccatgtgtggtcactacgtc
tgccacatcaagaaagaaggcagatgggtgatctacaatgaccagaaagtgtgtgcctcc
gagaagccgcccaaggacctgggctacatctacttctaccagagagtggccagctaa

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (9)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (35)   
   RefSeq(nuc) (15)   
   GenBank (10)   
   EMBL (10)   
3D Structure (12)   
   PDB (12)   
Protein domain (7)   
   Pfam (7)   
All databases (95)   

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